In 2006, a list of over 200 substances for evaluation was drawn up as part of Canada’s Chemical Management Plan. Over the past 10 years, these substances have been assessed in small batches for their impact on human health and the environment.
In December 2016, three of these substances were added to Schedule 1 of the Canadian Environmental Protection Act (CEPA).
Solvent red 23: This material is used as a colourant in cosmetics, as well as commercial hard surface disinfectants and pesticides. No personal care products regulated as drugs have been identified as containing Solvent red 23. After investigation, it was found that it becomes toxic after its chemical bonds break and release the carcinogen 4-aminoazobenzene. Before its ban, exposure through cosmetics was very low and only legal in products not intended to come into contact with mucous membranes. In Canada, it could only be imported, not manufactured. There was not determined to be any adverse environmental impacts caused by Solvent red 23.
Also known as: 2-naphthalenol 1-[[4-(phenylazo)phenyl]azo] C12H16N4O INCI: C126100
DEHA: In April 2014, Health Canada added DEHA (Di(2-ethylhexyl) adipate) to the list of prohibited and restricted cosmetic ingredients (the Cosmetic Ingredient Hotlist) due to the identification of developmental effects caused by the substance. Recent evaluation deemed it to be harmful to human health based on the concentrations that Canadian consumers are exposed to, particularly through personal care products and heavy duty hand cleansers. It was originally thought that it was also an environmental risk for its potential to harm aquatic organisms, but it was later determined that the current concentration in the aquatic environment is below the level likely to be harmful. Also known as: hexanedioic acid bis(2-ethylhexyl) ester C22H42O4
Prepod: This is actually several substances which are the reaction products of 2-propanone and diphenylamine. Prepod consists of numerous components with varying concentrations depending on how the reaction is carried out. One of these components, DIPDMA (diisopropyldimethylacridan) accumulates in organisms and may increase in concentration within food chain. It was therefore deemed harmful to environment. However, there is no evidence of Prepod being dangerous for human health at current exposure levels.
The addition of these materials to the Toxic Substances List will allow the government to develop regulations in order to mitigate possible risks associated with their use.
If you have any questions, please feel free to contact Focal Point Research. We are industry leading Canadian Cosmetic Regulatory Consultants that you can trust to help guide your company in the right direction.